Left adrenal hepatocellular carcinoma recurrence in liver transplanted patient

  • Tommaso Maria Manzia
Keywords: Liver Transplantation, Adrenal metastases after liver transplantation, Hepatocellular carcinoma recurrence


Hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) has been reported in less than 20% of patients fulfilling Milan Criteria. Mostly, it occurs on the liver, lungs, lymph nodes, bones and brain. A 45 years old Caucasian man affected by HCV-related liver cirrhosis with HCC, who underwent several multi-modal treatments, including hepatic resection, liver transplantation and loco regional treatment presented in our Department with an unusual mass within the left adrenal gland. patient underwent left adrenelectomy and the final histological findings showed feautures of HCC.

This case shows that extremely rare sites of HCC metastases have to be always investigated, especially if, despite all carry out treatments, still persist a clinical or laboratory suspect of HCC recurrence.